Importance of prebiotic and probiotic: the role of galactooligosacharides as prebiotic additives: a review
Abstract
In today's well-resistant pathogens and excessive use of antibiotics which weake and undermine the immune system the importance of pre- and probiotics is more desired. Probiotics - lactic acid bacteria - our intestinal symbiotes, has significant affect on our intestinal tract and brings us to number of positive physiological effects – inhibit the development of pathogenic microflora and serious stimulate the immune system, which subsequently leads to secondary health benefits - efficient use of energy from food, better resorption of minerals and vitamins by intestinal epithelium, suppression of diseases and inflammatory processes in the human intestine and many others. This article discusses the impact of prebiotics (essential substrate for probiotic bacteria), but also natural occurrence and important of prebiotics. Galactooligosaccharides (GOS) as prebiotic are the most suitable and therefore their commercial application is discussed.
doi:10.5219/251
References
Bosscher, D., Van Loo, J., Franck A. 2006. Inulin and oligofructose as functional ingredients to improve bone mineralization. Int. Daily J., vol. 16, p. 1092-1097. http://dx.doi.org/10.1016/j.idairyj.2005.10.028
Clementel A. 2012. Probiotics and Prebiotics: An Update from the World Gastrointestinal Organization (WGO). Eur. J. Food Res. Rev., vol. 2, no. 1, p. 24-28.
Dreamfieldsfoods, 2012. Diet information [online] s.a. [cit.20.04.2012] Retrieved from the web: http://www.dreamfields foods.com/diet-information.html# term0002.
FDA, 2012. Guidlenes for the evaluation of probiotics in food [online] s.a. [cit.29.06.2012] Retrieved from the web: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-rpt0282-Tab-03-Ref-19-Joint-FAOWHO-vol219.pdf? utm_campaign=Google2&utm_source=fdaSearch&utm_medium=website&utm_term=probiotic&utm_content=8.
FreeLibrary, 2011. Townsed Leeter (January 1, 2011): Symposium highlights immune function: probiotics, prebiotics, and enzymes. Retrieved from the web: http://www.thefreelibrary.com/Symposium+highlights+Immune+Function%3A+probiotics,+prebiotics,+and...-a0246017454.
Galbavý, Š., Bobek, P., Szifrusz, A. 2008. Pleuran, prebiotiká a ovplyvnenenie civilizačných chorôb. Experimentálne štúdie. KT Komárno, 151 p. ISBN 8080566210.
Gibson, G. R., Rastal, R. A. 2006. Prebiotics: Development & Application. John Wiley & Sons Ltd, England. http://dx.doi.org/10.1002/9780470023150
Gibson, G. R., McCartney, A. L., Rastall, R. A. 2005. Prebiotics and resistance to gastrointestinal infections. Br. J. Nutr., vol. 93, p. 31-34. http://dx.doi.org/10.1079/BJN20041343
Herich, R., Levlit, M. 2002. Lactic acid bacteria, probiotics and immune system. Vet. Med. - Czech, vol. 47, p.169-180.
Livestrong, 2012. Probiotics for diabetics [online] s.a. [cit.21.06.2012] Retrieved from the web: http://www.livestrong.com/article/492618-probiotics-for-diabetics/.
Ma, E. L., Choi, Y. J., Choi, J., Pothoulakis, C., Rhee, S. H., Im, E. 2010. The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibition. Int. J. Cancer vol. 127, no. 4, p. 780-790. http://dx.doi.org/10.1002/ijc.25011, PMid:19876926
Mannucci, F. 2009. Enzymatic synthesis of galactooligosaccharides from whey permeate. Dublin Institute of Technology.
Nutricialmedical, 2012. Prebiotická vláknina [online] s.a. [cit.08.04.2012] Retrieved from the web: http://www.nutriciamedical.cz.prebioticka_vlaknina.
Ooi, L. G., Loing, M. T. 2010. Cholesterol-lowering effects of probiotics and prebiotics: A review of in vivo and in vitro findings. Int. J. Mol. Sci., vol. 11, p. 2499-2522. http://dx.doi.org/10.3390/ijms11062499 PMid:20640165
Park, A. R., Oh, D.K. 2010. Galacto-oligosaccharide production using microbial β-galactosidase: current state and perspectives. App. Microbiol. Biotechnol., vol. 85, p. 1279-1286. http://dx.doi.org/10.1007/s00253-009-2356-2 PMid:19943044
Patentgenius, 2012 Patent 5604127 [online] s.a. [cit.02.07.2012] Retrieved from the web: http://www.patentgenius.com/patent/5604127.html.
Pigeonmania, 2012. Probiotics for racing pigeons [online] s.a. [cit.02.07.2012] Available at: Retrieved from the web: http://www.pigeonmania.com/probiotics-for-racing-pigeons/.
Perdigón, G., Fuller, R., Raya, R. 2001. Lactic acid bacteria and their effect on the immune system. Curr. Issues Intest. Microbiol., vol. 2, p. 27-42. PMid:11709854
Sagwan, V., Tomar, S. K., Singh, R. R. B., Singh, A. K., Babar, A. 2011. Galactooligosaccharides: Novel Components of Designer Foods. J. Food Sci. vol 76, no. 4, p. 103-111. http://dx.doi.org/10.1111/j.1750-3841.2011.02131.x PMid:22417365
Saini, R., Saini, S., Sharma, S. 2010. Potential of probiotics in controlling cardiovascular diseases. J. Cardiovasc. Dis. Res., vol. 1, p. 213-214. http://dx.doi.org/10.4103/0975-3583.74267 PMid:21264188
Steer, T., Carpenter, H., Tuohy, K., Gibson, G. R. 2000. Perpectives on the role of the human gut microbiota and its modulation by pro- and prebiotics. Nutr. Res. Rev. vol. 13, p. 229-254. http://dx.doi.org/10.1079/095442200108729089 PMid:19087441
Toma, M. M., Pokrotniek, S. J. 2006. Probiotics as functional food: Microbiological and medical aspects. Acta Universitatis Latviensis, vol. 710, p. 117-129.
Tores, D. P. M., Conclaves, M. P. F., Teixeira, J. A., Rodrigues, L. R. 2010. Galacto-oligosaccharides: production, properties, applications and significance as prebiotics. Compr. Rev. Food Sci. F., vol. 9, p. 438-454.
http://dx.doi.org/10.1111/j.1541-4337.2010.00119.x
Wallace, T. C., Guarner, F., Madsen, K., Cabana, M. D., Gibson, G., Hentges, E., Ssanders, M. E. 2011. Human gut microbiota and its relationship to health and disease. Nutr. Rev., vol. 69, p. 392-403. http://dx.doi.org/10.1111/j.1753-4887.2011.00402.x PMid:21729093
Wang, Z., Klipfell, E., Bennett, B. J., Koeth, R., Levison, B. S., GuGar, B., Feldstein, A. E., Britt, E. B., Fu, X., Chung, Y.-M., Wu, Y., Schauer, P., Ssmith, J. D., Allayee, H., Wilson, Tang, W. H., DiDonato, J. A., Lusis, A. J., Hanzen, S. L. 2011. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature, vol. 472, p. 7341-57. http://dx.doi.org/10.1038/nature09922 PMid:21475195
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